Copyright © 1998
Aribert Deckers
and
Copyright © 1998
Antares Real-Estate

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Burrascano and Plaquenil / Zithromax



Autor: Palund
Email: monkeypa@dircon.co.uk
Datum: 30.10.1995
Forum: sci.med.diseases.lyme

This is copied from a treatment recommendation for chronic Lyme:

Dr. Josepth Burrascano, Jr. M.D.
East End Medical Assoc. P.C.
139 Springs Fireplace Road
East Hampton, N.Y. 11937


                     TREATING INTRACELLULAR LYME


ZITHROMAX  (azithromycin)

This antibiotic is related to erythromycin.  When used in combination with
Plaquenil, it can potentially kill spirochetes that have not been able to
be touched by antibiotics before, and therefore can make a big difference
in treating chronic Lyme.


   Take one daily for the first week, then raise the dose to two daily.

   Take the two together as a single dose one hour before or three hours
after food.

   I recommend you take them as soon as you get up in the morning, then
wait one hour before you have breakfast.


PLAQUENIL  (hydroxychloroquine)

This quinine based drug can help prevent the antibiotic from being
inactivated before it can kill the spirochete.

   Take 3 pills daily as separate doses, with food or milk for 7 days
(loading dose).

   Then cut the dose to 2 pills daily.

You will need an eye exam by an ophthalmologist as a baseline, then on a
regular basis while on this medication (at least every six months).

WHAT TO EXPECT WITH TREATMENT:

Plaquenil has anti-inflammatory qualities, and prevents severe Jarisch
-Herxheimer reactions.  However, do expect symptoms to flare during the
first two to four weeks.  The Herxheimers are often unusual, and involve
mainly neurologic symptoms as well as joint pain.  About one third of
patients experience diarrhea during this time.  If this happens, stop the
medication for two to three days then resume.  If this does not control
the bowels, stop the treatment and call.  It is extremely rare for this
combination to cause nausea or heartburn.



Autor: gary tietjen
Email: gary.tietjen@snet.net
Datum: 13.6. 1998
Forum: sci.med.diseases.lyme

Burrascano and Plaquenil

Hi All

I posted this yesterday but I did'nt see it come up on the list so I'll try 
again.


                     TREATING INTRACELLULAR LYME By

                          Joseph Burrascano



                             ZITHROMAX

This antibiotic is related to erythromycin.  When used in combination with 
plaquenil it can potentially kill spirochetes that have not been touched 
by antibiotics before, and therefore make a big difference treating chronic 
Lyme. 

Take one daily for the first week,then raise the dose to two daily. Take the 
two together as a single dose one hour before or three hours after food I 
recommend you take them as soon as you get up in the morning, then wait one 
hour before you have breakfast.


                             PLAQUENIL

This quinine based drug can help prevent the antibiotic from being 
inactivated before it can kill the spirochete.

Take 3 pills daily as separate doses with food or milk for 7 days (loading 
dose) Then cut the dose to 2 pills daily. You will need an eye exam by an 
opthamologist as a baseline, then on a regular basis while on this med. (at 
least every 6 months.) 



                    WHAT TO EXPECT WITH TREATMENT

Plaquenil has anti-inflammatory qualities, and prevents severe Herxheimer 
reactions.  However do expect symptoms to flare during the first 2 to 4 weeks. 
The herxheimers are often unusual and involve mainly neurologic symptoms 
as well as joint pains.  About one third of patients experience diarrhea 
during this time.  If this happens,stop the med. for 2 to 3 days then resume. 
If this does not control the bowels, stop the treatment and call. It is 
extremely rare for this combo to cause nausea or heartburn. 

I posted this yesterday but I did'nt see it come up on the list so I'm 
trying again.  
Margie



Autor: Cindi
Email: cindi@worldnet.att.net
Datum: 15.6.1998
Forum: sci.med.diseases.lyme

gary tietjen wrote:

> Hi All

> I posted this yesterday but I did'nt see it come up on
> the list so I'll try again.

> TREATING INTRACELLULAR LYME By
> Joseph Burrascano

> PLAQUENIL  This quinine based drug can help prevent the antibiotic from 
> being inactivated before it can kill the spirochete. Take 3 pills daily 
> as separate doses with food or milk for 7 days(loading dose)  Then cut 
> the dose to 2 pills daily

Just want to reiterate a point I made recently about Plaquenil being poorly 
tolerated. Not all MD's agree with the "loading dose" theory as 
some patients cannot tolerate it more than 1X per day. In some cases, it's 
easier to start with 1 dose and work up to 2 rather than following this 7 
day "loading dose" theory.

Also, this same post talked about taking Zithromax on an empty stomach. The 
new Zith doesn't require this, in fact the packaging states take with or 
without food. The old Zith required an empty stomach.

Cindi



Autor: Cindi
Email: cindi@worldnet.att.net
Datum: 19.6.1998
Forum: sci.med.diseases.lyme

The old Zithromax needed to be taken on an empty stomach.  The new one 
can be taken with food. It's not necessarily a dosing issue.  I'm on 250mg. 
2x/day and it can be taken with or without food.  I thought this was a 
misprint since zith was one of the first abx I took for Lyme several years 
back so I checked back with the pharmacy, then the MD.  Both explained it's 
a change in formula that doesn't require an empty stomach anymore.

Also, zith has a very long half-life and keeps high blood levels for up to 
72 hours after taken.  When you have to take it twice a day -- the 12 hours 
apart rule isn't as important as some other abx's.

Just stuff I've learned along the way.

Cindi


Woodi16 wrote:

> In article <1998061821421500.RAA09794@ladder03.news.aol.com>,
> rmagricola@aol.com (RMAgricola) writes:
>
> >Zithromax 250 mg. is to be taken on an empty stomach.  Zithromax 600 mg  is
> >to
> >be taken with food (Do not ask me why ).
>
> Is it not the other way around? I was on zith 600mg for well over a year, and I
> was always told to take it with an empty stomach. The one time (early on) that
> I didn't adhere to those directions, I was a sick pup!
>
> Marci

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Copyright © 1998
Aribert Deckers
and
Copyright © 1998
Antares Real-Estate